Effects of cysteamine hydrochloride and luteinizing hormone-releasing hormone analog on growth hormone secretion in Yellow-Fin Porgy

SHI He-rong; ZHANG Wei-min; LIU Xiao-chun; KE Hao; LIN Hao-ran

Article Contents

Article Navigation > Haiyang Xuebao > 2005 > 27(3): 147-153

SHI He-rong, ZHANG Wei-min, LIU Xiao-chun, KE Hao, LIN Hao-ran. Effects of cysteamine hydrochloride and luteinizing hormone-releasing hormone analog on growth hormone secretion in Yellow-Fin Porgy[J]. Haiyang Xuebao, 2005, 27(3): 147-153.

Citation:

PDF( 1977 KB)

Effects of cysteamine hydrochloride and luteinizing hormone-releasing hormone analog on growth hormone secretion in Yellow-Fin Porgy

1.
Institute of Aquatic Economic Animals and Guangdong Province Key Laboratory for Aquatic Economic Animals, Sun Yat-sen University, Guangzhou 510275, China;Veterinary Medicine Institute Guangdong Academy of Agricultural Sciences, Guangzhou 510640, China
2.
Institute of Aquatic Economic Animals and Guangdong Province Key Laboratory for Aquatic Economic Animals, Sun Yat-sen University, Guangzhou 510275, China
3.
Veterinary Medicine Institute Guangdong Academy of Agricultural Sciences, Guangzhou 510640, China

Received Date: 2004-03-03
Rev Recd Date: 2004-08-11

Abstract

Abstract

Effects of cysteamine hydrochloride (a somatostatin-inhibiting agent,CSH) and luteinizing hormone-releasing hormone analog on growth hormone secretion in Sparus latus were investigated by i.p.injection.The pituitary GH contents of Sparus latus were significantly increased 2 hposti.p.injection of CSH with doses of 25,50 and 100 g/gb.w,and returned to control levels 24 h post injection.The serum GH levels of Sparus latus were significantly increased 2 h post injection of CSH with dose of 100 g/gb.w,and 6 h post injection of CSH with doses of 25 and 50 g/gb.w; LHRH- A(0.1 g/gb.w) significantly increased pituitary GH contents and serum GH levels 2 h post injection.Combining injection of LHRH-A and CSH significantly increased pituitary GH contents 6 h post injection as compared with CSH or LHRH-A alone,and the serum GH levels were significantly increased 12 h post injection as compared with CSH or LHRH-A alone.These results indicate that both CSH and LHRH-A could stimulate the synthesis and release of GH in Sparuslatus,and the effects of CSH were dose dependent.The combined effects of CSH and LHRH-A were significantly higher than those of CSH or LHRH-A alone.
- cysteamine hydrochloride(CSH),
- LHRH-A,
- Sparus latus,
- growth hormone

FullText(HTML)

References(31)

References

CHANG Y S,LIU C S,HUANG F L,et al.The primary structures of growth hormone of three cyprinid species:bighead carp,silver carp,and grass carp[J].Gen Comp Endocrinol,1992,87(3):385-393.

林浩然.鱼类生长和生长激素分泌活动的调节(综述)[J].动物学报,1996,42(1):69-78.

徐斌,张培军,苗宏志,等.鱼生长乳素的分离纯化与N-末端序列分析[J].海洋学报,1998,20(2):83-89.

MCLEAN E,DONALDSON E M.The role of growth hormone in the growth of in poikilotherms[A].SCHRREIBMAN M P,SCANES C G,PANG P K T,et al.The Endocrinology of Growth,Development,and Metabolism in Vertebrates[C].San Diego:Academic Press,1993.43-71.

ETER R E,MARCHANT T A.The endocrinology of growth in carp and related species[J].Aquaculture,1995,129(1～4):299-321.

PENG C,PETER R E.Neuroendocrine regulation of growth hormone secretion and growth in fish[J].Zoologica Studies,1997,36(2):79-89.

林浩然.神经内分泌因子调控鱼生殖和生长的相互作用[J].动物学研究,2000,21(1):12-16.

MARCHANT T A,CHANG J P,NAHORNIAK C S,et al.Evidence that gonadotropin-releasing hormone also functions as a growth hormone-releasing factor in the goldfish[J].Endocrinology,1989,124(2):509-2 518.

林信伟,林浩然,张庆.促性腺激素释放激素类似物促进鱼类生长激素分泌和生长[J].水产学报,1993,17(4):282-288.

LIN H R,ZHANG Q,PETER R E.Effects of recombinant tuna growth hormone and analogs of gonadotropin-releasing hormone on growth of grass carp(Ctenopharyngodon idellus)[J].Aquaculture,1995,129(1～4):341-343.

林信伟,林浩然.鲑鱼促性腺激素释放激素(sGnRH)调节鲤鱼脑垂体生长激素分泌的离体研究[J].动物学报,1994,40(1):30-38.

王黎,林浩然.促黄体素释放激素类似物和多巴胺对鲤鱼幼鱼和性成熟雌鱼生长激素分泌的作用[J].动物学报,1997,43(3):303-308.

LIN Hao-ran,LU Min,LIN Xin-wei.Effects of gonadotropin-releasing homone(GnRH)analogs and sex steroids on growth hormone secretion in common carp(Cyprinus carpio) and grass carp(Ctenopharyngodon idellus)[J].Aquaculture,1995,135(1～3):173-184.

邓利,林浩然.腹腔注射LHRH A对黑鲷生长激素及其受体的影响(J).深圳大学学报(理工版),2003,20(2):60-65.

温海深,林浩然,肖东,等.野生鲇鱼生长激素分泌的季节变化及其神经内分泌调控[J].动物学报,2002,48(2):213-220.

HALL T R,HARVEY S,SCANES C G.Control of growth hormone secretion in the vertebrates,a comparative survey[J].Comp Biochem.Physiol,1986,84(2):231-253.

刘均利.半胱胺耗竭体内生长抑素及其机制[J].生理科学进展,1990,21(3):271-274.

XIAO Dong,LIN Hao-ran.Effeets of cysteamine-a somatostatin-inhibiting agent on serum growth hormone levels and growth in juvenile grass carp(Ctenopharyngodon idellus)[J].Comparative Biochemistry and Physiology(Part A),2003,134(1):93-99.

XIAO Dong,LIN Hao-ran.Effeets of cysteamine hydrochloride on growth hormone secretion from hypothalamus-pituitary tissue in juvenile grass carp(Ctenopharyngodon idellus)[J].2003,Acta Zoologica Sinica,49(5):600-605.

邓利,张为民,林浩然,等.黑鲷生长激素及其受体的季节变化[J].水产学报,2001,25(3):203-208.

MARCHANT T A,PETER R E.Hypothalamic peptides influencing growth hormone secretion in the goldfish Carassius auatus[J].Fish physiol Biochem,1989,7(1～4):133-139.

王黎,林浩然,张为民.阿扑吗啡对LHRH-A促进鲤鱼GtH和GH分泌的影响[J].中山大学学报(自然科学版),1997,36(1):119-121.

陈细华,陈松林,邓文涛.LHRH-A2及无机离子促进草鱼脑垂体离体分泌GH的初步研究[J].动物学杂志,1999,34(3):10-12.

PAPCHRISTOU D N,LIU J L,PATEL Y C.Cysteamine induced reduction in tissue somatostatin immuno-reactivity is associated with alterations in somatostatin mRNA[J].Regul Pept,1994,49(3):237-247.

SZABO S,REICHLIN S.Somatostatin in rat tissue is depleted by cysteamine administration[J].Endocrinol,1981,109:2 255-2 257.

KWOK R S,CAMERON J L,FALLER D V.Effects of cysteamine administration on somatostatin biosynthesis and levels in rat hypothanisms of action[J].Endocrinol,1992,131(6):2 999-3 009.

MILLARD W J,SAGAR S M,BADGER T M,et al.Cysteamine effects on growth hormone secretion in the male rats[J].Endocrinology,1983,112(2):509-517.

MCLEOD K R,HARMON D L,SCHILLO K K,et al.Effect of cysteamine on pulsatile growth hormone release and plasma insulin concentrations in sheep[J].CompBiochem Physoil(B),1995,112:523-533.

MCELWAIN K V,ESTIEMME M J,BARB C R.Effect of cysteamine hydrochloride on secretion of growth hormone in male swine[J].Life Sci,1999,64(24):2 233-2 238.

张为民,林浩然.草鱼血清生长激素水平的日变化[J].水产学报,1995,19(3):263-267.

陈松林,陈细华,牟松,等.草鱼的生长及其血清生长激素水平的季节和日变化规律的研究[J].水产学报,1998,22(1):23-27.

Relative Articles

Supplements(0)

Cited By

Proportional views