Benzo(a) pyrene and pyrene inducing DNA damage in <i>Mugil so-iuy</i>

Chen Yixin; Wang Chonggan; Li Qin; Liu Yan; Zheng Weiyun

Article Contents

Article Navigation > Haiyang Xuebao > 2000 > 22(2): 92-96

Chen Yixin, Wang Chonggan, Li Qin, Liu Yan, Zheng Weiyun. Benzo(a) pyrene and pyrene inducing DNA damage in Mugil so-iuy[J]. Haiyang Xuebao, 2000, 22(2): 92-96.

Citation:

Chen Yixin, Wang Chonggan, Li Qin, Liu Yan, Zheng Weiyun. Benzo(a) pyrene and pyrene inducing DNA damage in Mugil so-iuy[J]. Haiyang Xuebao, 2000, 22(2): 92-96.

Chen Yixin, Wang Chonggan, Li Qin, Liu Yan, Zheng Weiyun. Benzo(a) pyrene and pyrene inducing DNA damage in Mugil so-iuy[J]. Haiyang Xuebao, 2000, 22(2): 92-96.

Citation:

Chen Yixin, Wang Chonggan, Li Qin, Liu Yan, Zheng Weiyun. Benzo(a) pyrene and pyrene inducing DNA damage in Mugil so-iuy[J]. Haiyang Xuebao, 2000, 22(2): 92-96.

PDF( 382 KB)

Benzo(a) pyrene and pyrene inducing DNA damage in Mugil so-iuy

1.
Department of Biology, Xiamen University, Xiamen 361005
2.
Research Center for Environmental Sciences, Xiamen University, Xiamen 361005

Received Date: 1999-09-20
Rev Recd Date: 1999-11-25

Abstract

Abstract

Mugil so-iuy was exposed to benzo(a)pyrene, pyrene and their mixture of equal quantity, at concentration of 0.1, 1, 10, 20 μg/dm³ and 50μg/dm³ respectively. After 5 d, the DNA damage of the liver and the gill was measured respectivety by alkaline unwinding assay. The result showed that DNA damage of the liver was increased as the concentrations of pollutants increased. At the same concentrations, the mixture of benzo(a) pyrene and pyrene induced grarer damage to DNA than benzo(a) pyrene or pyrene separately did. The united effect of benzo(a) pyrene and pyrene would be potentiated.
- Benzo(a) pyrene,
- pyrene,
- DNA damage,
- .Mugil so-iuy,
- alkaline unwinding

FullText(HTML)

References(12)

References

徐立红,张甬元,陈宜瑜．分子生态毒理学研究进展及其在水环境保护中的作用．水生生物学报,1995．19(2):171～185

Shugart L R. Quantitation of chemically induced damage to DNA of aquatic organisms by alkaline unwinding. Aquatic Toxicology, 1988, 13:43～52

Bihari N, Batel R, Zahn R K. Fraction action of DNA from marineinvertebrate (Maja crispata, mytilus galloprovincialis) haemolymph by alkaline elution. Comp Bioch em Physiol, 1992, 102B:419～424

Vukmirovic M, Bihari N, Rudolf K, et al. DNA damage in marine mussel Mytilus galloprovincialis as a biomarker of environmental contamination. Marine Ecology Progress Series, 1994, 109:165～171

Everaarts J M, Sarkart A. DNA damage as a biomarker of marine pollution: strand breaks in seastarts (Asterias rubens) from the North Sea. Water Science and Technology, 1996, 34:7～8.

刘发义,孙凤．石油污染对梭鱼肝脏混合功能氧化酶的影响．海洋环境科学,1991,10(3):49～51

赵云英,马永安．天然环境中多环芳烃的迁移转化及其对生态环境的影响．海洋环境科学．1998,17(2):68～72

Steinert S A, Montee R S, Sastre M P. Influence of sunlight on DNA damage in mussels exposed to polycyclic aromatic hydrocarbons. Marine Environmental Research. 1998,46,1～5

靳波,邱云峰．大鼠和人胎肝\肺微体酶对苯并(a)芘代谢的研究.卫生毒理学杂志,1992,6(4):273～274

童建,冯致英编著.环境化合物的联合毒作用．上海:上海科学技术文献出版杜,1994 105:204

Otto D M E, Moon T M. Phase 1 and 2 enzymes and antioxidant responses in rainbow trout exposed to PCB contanmined sediments in the St. Lawrence River. Chemosphere, 1996, 33(10):2 021～2032

Sugg D W, Chesser R K, Grasman B T. The association of DNA damage to concentration of mercury and radiocesium in large mouth bass. Environmental Toxicology and Chemistry, 1995, 14(4):661～668

Relative Articles

Supplements(0)

Cited By

Proportional views