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Sang Benhong, Xu Xiaojin, Mao Yong, Wang Jun, Su Yongquan. Detection of macrophage migration inhibitory factor in Vibrio alginolyticus disease of Larimichthys crocea tissues and its significance[J]. Haiyang Xuebao, 2014, 36(8): 111-116. doi: 10.3969/j.issn.0253-4193.2014.08.012
Citation: Sang Benhong, Xu Xiaojin, Mao Yong, Wang Jun, Su Yongquan. Detection of macrophage migration inhibitory factor in Vibrio alginolyticus disease of Larimichthys crocea tissues and its significance[J]. Haiyang Xuebao, 2014, 36(8): 111-116. doi: 10.3969/j.issn.0253-4193.2014.08.012

Detection of macrophage migration inhibitory factor in Vibrio alginolyticus disease of Larimichthys crocea tissues and its significance

doi: 10.3969/j.issn.0253-4193.2014.08.012
  • Received Date: 2013-08-09
  • Rev Recd Date: 2013-11-27
  • To investigate the expression and prognostic value of macrophage migration inhibitory factor (MIF) in Vibrio alginolyticus disease of Larimichthys crocea tissues. MIF expression was detected by immunohistoehemistry in spleen,intense and head kidney specimens of pathologically identified and healthy L.crocea tissues. All negative controls showed no reactivity,MIF staining was intense in V.alginolyticus disease of L.crocea tissues. The spleen,intense and head kidney specimens showed high reactivity in an upward trend.The MIF staining rate of the spleen,intense and head kidney were 56%,64% and 92%.The high MIF expression in the disease tissues indicate that MIF plays an important role in the homeostatic process of V.alginolyticus challenged with L.crocea.
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