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三丁基锡对褐菖鲉(Sebastiscus marmoratus)体内苯并(α)芘代谢的影响

郑榕辉 赵扬 陈奕欣 左正宏 王重刚

郑榕辉, 赵扬, 陈奕欣, 左正宏, 王重刚. 三丁基锡对褐菖鲉(Sebastiscus marmoratus)体内苯并(α)芘代谢的影响[J]. 海洋学报, 2007, 29(4): 165-169.
引用本文: 郑榕辉, 赵扬, 陈奕欣, 左正宏, 王重刚. 三丁基锡对褐菖鲉(Sebastiscus marmoratus)体内苯并(α)芘代谢的影响[J]. 海洋学报, 2007, 29(4): 165-169.
ZHENG Rong-hui, ZHAO Yang, CHEN Yi-xin, ZUO Zheng-hong, WANG Chong-gang. Effects of tributyl tin on the metabolism of benzo(a)pyrene in Sebastiscus marmoratus[J]. Haiyang Xuebao, 2007, 29(4): 165-169.
Citation: ZHENG Rong-hui, ZHAO Yang, CHEN Yi-xin, ZUO Zheng-hong, WANG Chong-gang. Effects of tributyl tin on the metabolism of benzo(a)pyrene in Sebastiscus marmoratus[J]. Haiyang Xuebao, 2007, 29(4): 165-169.

三丁基锡对褐菖鲉(Sebastiscus marmoratus)体内苯并(α)芘代谢的影响

基金项目: 国家自然科学基金项目资助(20447001);福建省自然科学基金项目资助(D0410007)

Effects of tributyl tin on the metabolism of benzo(a)pyrene in Sebastiscus marmoratus

  • 摘要: 在水生毒理学研究中,污染物与污染物之间的相互作用是一个重要的课题.苯并(α)芘[benzo(α)pyrene,BaP]是一种具有致癌性的多环芳烃(poly-cyclic aromatic hydrocarbon,PAH),而三丁基锡(tributyl tin,TBT)则是用于防污涂料的具有很强毒性的有机金属.许多化学物进入生物体内后的转化分为两个阶段.在Ⅰ相反应阶段,亲脂性底物被氧化代谢形成各种中间代谢物,这些中间代谢物具有很高的生物活性,容易对生物体产生毒性.
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  • 收稿日期:  2005-11-20
  • 修回日期:  2006-06-30

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