石鲽卵巢雌二醇及其受体和睾酮受体免疫组织化学研究

温海深; 高玲

石鲽卵巢雌二醇及其受体和睾酮受体免疫组织化学研究

温海深,
高玲

中国海洋大学, 海水养殖教育部重点实验室, 山东, 青岛, 266003

基金项目: 农业部海洋水产增养殖学与生物技术重点开放实验室基金资助(K2003-02)

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出版历程
- 收稿日期: 2006-08-29
- 修回日期: 2006-12-12

Studies on immunohistochemical response of testosterone receptors and estradiol and its receptors in stone flounder(Kareius bicoloratus)

Key Laboratory of Mariculture, Ministry, Ocean University of China, Qingdao 266003, China

摘要

摘要: 细胞核的雌激素受体(ER)是参与调节脊椎动物发育和繁殖的转录因子,哺乳动物具有两种类型的ER(ER-α和ER-β),它们一旦与配体结合就能够形成二聚体,和其他转录激活因子相互作用,参与靶基因调节^[1].目前,在鱼类中发现3种ER类型,即ER-α,ER-β和ER-γ^[2~4],这说明鱼类ER生理功能比高等动物复杂,但对每种ER的功能研究较少.雄激素在脊椎动物(包括鱼类)的性别分化和性腺发育过程中起着十分重要的作用,一般认为这种作用是通过雄激素受体(AR)介导的^[5].AR属于配体活性转录因子,是核受体家族的一员^[6].
- 石鲽 /
- 卵巢 /
- 雌二醇 /
- 受体
- Kareius bicoloratus /
- ovary /
- estradiol /
- receptor

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参考文献(20)

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